Through Notice of Special Interest (NOSI): Administrative Supplement for Research and Capacity Building Efforts Related to Bioethical Issues (Admin Supp, Clinical Trial Optional), NIAID will accept administrative supplement applications from current recipients for projects that focus on ethical, legal, and social implications (ELSI) research relevant to NIAID’s scientific mission: HIV/AIDS or its comorbidities (e.g., tuberculosis, malaria, hepatitis, sexually transmitted infections); infectious diseases including those transmitted by vectors, immunologic and allergic diseases, or organ transplantation; and ELSI of clinical trials and implementation science.
Keep in mind, only active grant recipients are eligible to apply.
You may include conceptual work in bioethics, or empirical work gathering and analyzing data relevant to ethical issues in research, or a combination of the two. For empirical projects, data collection may include quantitative or qualitative methods, or both.
Research Objectives
We are especially interested in the following topics:
- Research involving adolescents and young adults, including autonomy and informed consent.
- Policy issues at the intersections of public health surveillance, care delivery, and research.
- Issues within NIAID’s mission that are unique to child-bearing age and pregnant people.
- Enhanced engagement of key populations in research on HIV prevention, treatment, cure; HIV-related comorbidities and co-infections including those transmitted via sexual contact; improving dissemination, communication of results, mitigating barriers to research participation.
- Representation of key populations in research on immune-mediated diseases and transplantation for disease prevention, treatment, and/or cure; improving dissemination, communication of results, and mitigating barriers.
- Community engagement and attitudes concerning novel vector control measures, vaccines, other mitigation strategies for infectious diseases, and organ transplantation, including xenotransplants.
- Informing study designs for safety and efficacy evaluations of interventions, best practices for development and uptake of future therapeutics and/or prevention strategies.
- Best methods for securing highly sensitive data, including genetic data; risks from data breaches and reidentification; effective tools for anonymizing sensitive data; stakeholders’ attitudes toward data sharing methods and policies.
- Bioethical issues associated with the potential for genome editing to correct heritable traits and genetic disorders.
This list is not meant to be exhaustive; you may propose other bioethical research topics appropriate to NIAID’s mission.
Upon receipt of your application, NIH staff will consider whether the proposed supplement activities fit within the parent award’s original scope of award (i.e., the supplement cannot depart from the parent award’s scope).
Budget and Project Period
Application budgets are limited to $100,000 in direct costs. In addition to the direct cost, you may request applicable facilities and administrative (indirect) costs. Your budget request may be for 1 year of support only.
To apply, use the following notice of funding opportunity (NOFO) or its subsequent reissued equivalent:
Follow all instructions in the NOFO and the SF 424 (R&R) Application Guide and include “NOT-OD-24-031” (without quotation marks) in the Agency Routing Identifier field (box 4B) of the SF 424 R&R form. Applications without this information in box 4B will not be considered for this initiative.
Upon applying, notify the program officer listed on your current Notice of Award (i.e., the parent grant) that you submitted an application in response to this NOSI.
Applications are due on April 1, 2024, by 5 p.m. local time of the applicant organization.
Direct inquiries to Joana Roe, NIAID’s scientific/research contact for the initiative at joana.roe@nih.gov or 240-627-3213.