Consider applying to the reissued notice of funding opportunity (NOFO) Intervention Research to Improve Native American Health (R01, Clinical Trial Optional) if your research focuses on interventions to improve health in Native American populations.
This includes 1) etiologic research that will directly inform intervention development or adaptations; 2) research that develops, adapts, or tests interventions for health promotion, prevention, treatment, or recovery; and 3) where a sufficient body of knowledge on intervention efficacy exists, research on dissemination and implementation that develops and tests strategies to overcome barriers to the adoption, integration, scale-up, and sustainability of effective interventions.
Through this initiative, we seek intervention and related research to build upon community knowledge, resources, and resilience to identify and rigorously test culturally appropriate solutions to reduce morbidity and mortality. You should design interventions with consideration for sustainability within the communities where they are tested, and with the flexibility to be readily adapted, disseminated, and scaled up to other communities where culturally appropriate.
This NOFO is part of the Intervention Research to Improve Native American Health (IRINAH) initiative, which also includes NOFOs using the R21 Exploratory/Developmental Research Grant mechanism (PAR-23-299) and the Clinical Trial Planning Grant mechanism (PAR-23-285). Note that NIAID does not participate in those two NOFOs.
NIAID is interested in culturally appropriate applications focused on allergic, autoimmune, and infectious diseases research. Priority areas of research for NIAID include the following examples. See the NOFO for a complete list.
- Innovative strategies to scale up HIV prevention, including pre-exposure prophylaxis and other HIV prevention services in conjunction with care for sexually transmitted infections (STIs), mental health/substance use, and reproductive health using Native American appropriate approaches.
- Studies to understand HIV transmission, including studies to identify important risk factors in the Native American context and how to intervene to reduce HIV incidence.
- Research to evaluate the full context of HIV risk particularly as it relates to communities of risk versus individual risk behaviors and how to implement interventions at the community as well as the individual level. Studies that utilize data science, network analysis, and geographic analysis are of particular interest.
- Research on STIs in Native American populations, including 1) research to understand risk factors and population dynamics that promote transmission of STIs, to include but not be limited to syphilis, gonococcal, and chlamydial infections; 2) studies to improve detection, diagnosis, and treatment strategies of STIs, most importantly for congenital syphilis; and 3) implementation of STI prevention strategies.
- Research to test innovative strategies to improve diagnosis, prevention, and treatment of tuberculosis.
- Studies to understand the immunologic basis of asthma and allergic disease in Native American populations, including studies to identify important risk factors and how to intervene to mitigate disease morbidity.
Application budgets are not limited but need to reflect the actual needs of the proposed project.
Note that applicants requesting $500,000 or more in direct costs in any 1 year (excluding consortium facilities and administrative costs) must contact a scientific/research contact at least 6 weeks before submitting the application and follow the Policy on the Acceptance for Review of Unsolicited Applications that Request $500,000 or More in Direct Costs as described in the SF 424 (R&R) Application Guide.
NIAID’s scientific/research contact for this NOFO is Annalise Schoonmaker. You may reach her at annalise.schoonmaker@nih.gov or 240-669-5577.