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Measuring Innovation: Laboratory Infrastructure to Deliver Essential HIV Clinical Trial Results

HIV clinical trials network laboratory functions will continue to evolve to align with scientific priorities and research approaches.

Sequencing of Congo Mpox Reports Highlights New Transmission Patterns in Country

Laboratory analysis in the Republic of Congo showed mpox was affecting people in parts of the country where it has not been historically. The findings point to increases in human-to-human transmission across the border with the neighboring Democratic Republic of the Congo, where a large outbreak was declared a public health emergency of international concern.

Sexually Transmitted Infections—A Closer Look at NIAID Research

Sexually transmitted infections (STIs) are caused by bacteria, viruses, or parasites. NIAID supports research across the spectrum from basic to clinical science to develop effective diagnostic, preventive and therapeutic approaches to STIs in alignment with the National STI Strategic Plan. In recognition of National STI Awareness Week, NIAID shares a snapshot of new projects and recent scientific advances in STI research.

The STOMP Trial Evaluates an Antiviral for Mpox

NIAID launched the STOMP trial to determine whether the antiviral drug tecovirimat can safely and effectively treat mpox. In a video, Dr. Cyrus Javan of NIAID's Division of AIDS explains the importance of the STOMP trial.

NIAID Study Describes Immune Response to Mpox in Woman Living with HIV

Mpox has been present in west, central and east Africa for decades, with the first human case identified in 1970. In May 2022, a global mpox outbreak caused by a specific strain of the virus (referred to as “clade IIb”) was the first epidemiologic evidence of community mpox transmission outside of the historically affected African regions. More than 80,000 cases and 140 mpox-related deaths have...

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