7 Results
Vaccine Protective Against H5N1 Influenza from Cattle
Experimental H5N1 vaccine fully protective in mice against virus circulating in U.S. cattle.

Subclinical Disease in Monkeys Exposed to H5N1 by Mouth and Stomach
Drinking raw milk contaminated with H5N1 virus can cause infection but may be less severe. Regardless, exposure by raw milk should be avoided.

NIAID Research Key to H5N1 Influenza Preparedness Efforts
H5N1 influenza viruses have been around for years, but the spring 2024 outbreak of a highly pathogenic H5N1 avian influenza among U.S. dairy cows prompted new concerns. NIAID scientists and NIAID-funded researchers have been working closely to monitor the outbreak, understand spread among animals and develop potential prevention and treatment methods as part of larger U.S. government pandemic preparedness efforts.

Calling for Reinforcements: A New Way to Recruit Immune System Helpers Could Lead to Better Flu Vaccines
Flu causes hundreds of thousands of deaths and millions of hospitalizations worldwide. The best way to protect against serious illness is annual vaccination, but the vaccine’s effectiveness is not perfect. Now, NIH-funded researchers at the Stanford University School of Medicine have taken a new approach to crafting flu vaccines that resulted, in lab tests, in a more broadly protective immune response compared to currently available vaccines.

HPAI Influenza Devastating Birds, Marine Mammals in Peru--Study Identifies Concerning Viral Mutations
NIAID-funded researchers working in Peru have signaled concern about the deaths of birds and marine mammals from highly pathogenic avian influenza (HPAI) that has been spreading globally.

Universal Influenza Candidate Vaccine Performs Well in Phase 1 Trial
Developing a universal influenza vaccine is a significant priority for NIAID scientists. Two new studies describe a unique candidate developed by NIAID's Vaccine Research Center that performed well in a Phase 1 clinical trial.

Close-up view of protein-complex structures could lead to better flu vaccines
A new understanding of vaccine components gained through electron microscopy and other direct visualization techniques could help scientists design more effective seasonal influenza vaccines.
