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NIH Study Shows Chronic Wasting Disease Unlikely to Move from Animals to People

May 17, 2024

A new study of prion diseases, using a human cerebral organoid model, suggests there is a substantial species barrier preventing transmission of chronic wasting disease (CWD) from cervids—deer, elk and moose—to people. The findings, from National Institutes of Health scientists and published in Emerging Infectious Diseases, are consistent with decades of similar research in animal models at the NIH’s National Institute of Allergy and Infectious Diseases (NIAID).

NIH Scientists Use Human Cerebral Organoid to Test Drug for Deadly Brain Disease

March 9, 2021

After establishing a human cerebral organoid system to study CJD, NIAID researchers have developed the model to screen drugs for potential CJD treatment.

Scientists Identify Locations of Early Prion Protein Deposition in Retina

January 29, 2021

The earliest eye damage from prion disease takes place in the cone photoreceptor cells according to a new NIH study of prion protein accumulation.