10 Results
NIH-Sponsored Trial of Lassa Vaccine Opens
March 17, 2025
An NIAID-sponsored clinical trial of an experimental vaccine to prevent Lassa fever has begun.
Topical Steroid Withdrawal Diagnostic Criteria Defined by NIH Researchers
March 14, 2025
Topical steroid withdrawal (TSW) results in dermatitis that is distinct from eczema and is caused by an excess of NAD+, an essential chemical compound in the body, according to a new study from NIAID researchers.
Tecovirimat Is Safe but Ineffective as Treatment for Clade II Mpox
March 12, 2025
Monotherapy with the antiviral drug tecovirimat was safe but ineffective as an mpox treatment in an international clinical trial.
Omalizumab Treats Multi-Food Allergy Better than Oral Immunotherapy
March 3, 2025
The high rate of allergic reactions and other intolerable side effects of oral immunotherapy in the NIH-funded trial explained the superiority of omalizumab.
NIH-Funded Clinical Trial Will Evaluate New Dengue Therapeutic
February 11, 2025
A Phase 2 clinical trial will test the safety and efficacy of an experimental treatment for dengue, a viral disease transmitted by mosquitoes.
Single Dose of Broadly Neutralizing Antibody Protects Macaques from H5N1 Influenza
February 11, 2025
A single dose of a broadly neutralizing antibody given prior to virus exposure protects macaques from severe H5N1 avian influenza, NIH scientists report.
Influenza A Viruses Adapt Shape in Response to Environmental Pressures
February 10, 2025
Influenza A virus particles strategically adapt their shape – to become either spheres or larger filaments – to favor their ability to infect cells depending on environmental conditions, a new NIAID study published in Nature Microbiology reveals. This previously unrecognized response could help explain how influenza A and other viruses persist in populations, evade immune responses, and acquire adaptive mutations. The scientists designed the study to determine why many influenza A virus particles exist as filaments, which requires more energy to form than a sphere.
Therapy Helps Peanut-Allergic Kids Tolerate Tablespoons of Peanut Butter
February 10, 2025
Eating slowly increasing amounts of peanut butter enabled 100% of kids with peanut allergy to consume 3 tablespoons of peanut butter without an allergic reaction.
As Prevention Strategy for Sexually Transmitted Infections Rolls Out, Experts Highlight both Promise and Knowledge Gaps
January 6, 2025
DoxyPEP is reducing the rate of syphilis and chlamydia but has had little to no effect on gonorrhea and needs close monitoring for antibiotic resistance.
NIH Researchers Discover Novel Class of Anti-Malaria Antibodies
January 3, 2025
New antibodies that bind to a previously untargeted portion of the malaria parasite could lead to new monoclonal antibody treatments and vaccines for malaria.
