Biologist
Languages Spoken: Mandarin
Biography
Generated humanized mouse models, compared immune system development and function in NRG mice either transplanted with hematopoietic stem cells or transferred with PBMC from ICL patients or healthy controls. Characterized the presence of anti-lymphocyte antibodies in ICL patients, as well as the antibody functional capability of inducing antibody-dependent cell-mediated cytotoxicity (ADCC), complement deposition and complement-dependent cytotoxicity (CDC). Using a flow-based method to detect anti-lymphocyte antibodies and complement deposition in COVID-19 patients’ plasma and their PBMCs.