Michele Di Mascio, Ph.D.

Biography

Dr. Di Mascio is the Chief of the AIDS Imaging Research Section of the Integrated Research Facility and the Chief of the Mathematical Biology Section of the Biostatistics Research Branch at the Division of Clinical Research of NIAID. After his postdoctoral research work at the Theoretical Division of the Los Alamos National Laboratory of Los Alamos, New Mexico, he moved to NIH (in 2003), where he developed the first core laboratory facility in the agency to perform in vivo imaging studies of nonhuman primate models of simian/simian-human immunodeficiency virus (SIV/SHIV) infection. Dr. Di Mascio’s main areas of research are the dynamics of CD4 T cell depletion and reconstitution, viral replication, and virus-induced immune activation, antiviral drug distribution in the whole body of SIV/SHIV-exposed nonhuman primates using single-photon emission computed tomography (SPECT), positron emission tomography (PET), and computed tomography (CT) imaging technologies.