Alfred Agbekudzi, Ph.D.

Postdoctoral Fellow

Contact: For contact information, search the NIH Enterprise Directory.

Education:

B.S., Biochemistry Cell and Molecular Biology, 2015, University of Ghana, Legon

Ph.D., Biological Sciences, 2023, Virginia Tech, Blacksburg

Languages Spoken: Twi, Ewe

Biography

DprE1 is a crucial enzyme involved in the cell wall biosynthesis of Mycobacterium tuberculosis and is a target for the antituberculosis drug quabodepistat. I am working to elucidate the structure of DprE1 when bound to quabodepistat. In addition, I am interested in investigating collateral resistance and susceptibility phenotypes to other tuberculosis drugs in the presence of quabodepistat-resistant strains.