Scientists Developed a System of Organoids That Can Model Activity in B Cells

NIAID-funded scientists developed a system of organoids—lab-grown, miniature organ mimics—that can model activity in immune cells called B cells. The organoids were able to produce antibodies in response to influenza vaccines and act as a model for B cell-related disorders. According to the researchers, the organoids could be used to predict immune responses in healthy people and people with weakened immune systems. The findings were published in Nature Materials. 

Learn more in the publication, Human immune organoids to decode B cell response in healthy donors and patients with lymphoma.