Rules & Policies—Special Considerations

Standard Operating Procedures (SOPs) and resources regarding research involving human subjects, vertebrate animals, and select agents. Read more about research with special considerations.

Topic	SOPs and Policies
Human Subjects	Bars to Grant Awards SOP Bars to Grant Awards—Human Subjects SOP Clinical Terms of Award SOP Clinical Terms of Award Restriction for China Clinical Trial Monitoring SOP Data and Safety Monitoring Boards (DSMB) SOP Data Policy and Guidance Human Subjects Certifications—IRB or IEC SOP Human Subjects Federalwide Assurances SOP Human Subjects Research Requirements in Grants SOP Human Subjects Research Training SOP Inclusion Across the Lifespan in Human Subjects Research Policy SOP Investigator—Initiated Clinical Trial Administrative Extension SOP Investigator—Initiated Clinical Trial Planning and Implementation Awards SOP
Vertebrate Animals	Animals in Research for Grants SOP Bars to Grant Awards SOP Bars to Grant Awards—Research Animals SOP Model Organisms Sharing Complex Model Organisms Sharing Plan Model Organisms Sharing Plan for Mice Sharing Model Organisms SOP Simple Model Organisms Sharing Plan
Select Agents	Foreign Workers on NIH Awards SOP Select Agent Awards SOP

For Researchers