Vaccine Research Center Clinical Studies

The Vaccine Research Center evaluates candidate vaccines and monoclonal antibodies targeting HIV, influenza, Ebola, and other emerging infections.

Featured Studies

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Study of a Human Bispecific HIV Antibody (CAP256J3LS) in Healthy Adults

This is a study of an experimental product called CAP256J3LS. This study will provide more information about prevention or treatment of human immunodeficiency virus (HIV) infection.

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Experimental Influenza Vaccine (FluMos-v2) Study

Volunteering for this study will help us provide more information about flu vaccines that may one day lead to a universal flu vaccine that would be effective against all influenza strains.

Clinical Trials Sponsored by the Vaccine Research Center

The clinical trials and studies conducted by the Vaccine Research Center change frequently, but you can see a list of all current clinical trials and studies being conducted by VRC on our Find a Clinical Trial page.

View Trials

The Vaccine Research Center is looking for adults 18 years of age and older to participate in trials evaluating vaccine and monoclonal antibodies

Why Volunteer?

  • Help researchers develop potentially lifesaving vaccines
  • Contribute to the advancement of medicine
  • Provide researchers with important scientific information in a safe and confidential environment
  • Receive financial compensation for your time

How It Works

  • An independent committee reviews all VRC studies for safety, ethics, and need before approving them for volunteer participation.
  • When you contact the VRC, you will be asked a few questions about your health.
  • If you meet certain criteria, a screening visit is scheduled in which you will undergo a blood draw and physical examination to determine your eligibility for a vaccine study.
  • You will receive a consent form that explains the study in detail and in non-technical language.
  • By signing the consent form, you are indicating that you understand the study and that you volunteer to participate. As a volunteer, you are free to withdraw from the study at any time.
  • All volunteers are compensated for their participation.

Once you agree to participate, we will follow the steps below.

Informed Consent

  • You will have an initial interview.
  • We will tell you about the study in detail.
  • We will answer any questions you have to make sure that you understand everything involved with participating in our trial.
  • You will read and sign a consent form for the study.

Eligibility Screening

  • We will ask you to complete a health questionnaire.
  • You will receive a clinical exam that includes blood tests and a physical exam.

Vaccination

  • Over the period of a few weeks or months (depending on the trial), you will receive a vaccination or a series of vaccinations.
  • You will be asked to keep a record of any physical reaction you have to the vaccine.
  • We will monitor the effects of the vaccine through periodic blood tests.
  • You will also receive physical examinations while you are participating in the trial.

Volunteer for a Clinical Study

If you are interested in volunteering to participate in a clinical study, please call us at 866-833-LIFE (5433) or email us at vaccines@nih.gov. We will send you information about our clinical studies and follow up with you to answer any questions.

Or fill out the volunteer information form and we will match you with studies and contact you.

Volunteer Form

Read More About the Research

Learn more about the work being done at NIAID’s Vaccine Research Center.

What is it Like to Participate?

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Based on my personal experiences, I encourage people to look into the clinical trials at the VRC. You really cannot ask for nicer or more dedicated and knowledgeable staff than those at the VRC, and they appreciate all of their volunteers. Give it a shot and be a part of something truly important!

– Peter Hubbard

Read more about participating in the Participant's Guide to Clinical Trials

Read some Participant Testimonials to see more about what its like to participate.

You can also watch a series of short informational videos from Health and Human Services about participating in clinical trials.

Contact Information

For more information or to volunteer for a vaccine research study

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