Two molecules of restriction factor APOBEC3H form a sequence-independent complex with an RNA duplex.
Credit:
CRNA
Principal investigator: Alice Telesnitsky, Ph.D., University of Michigan
The CRNA comprises an integrated team of biophysicists, cell and computational biologists, chemists, and virologists dedicated to advancing understanding of the structures and molecular processes that involve RNA during HIV-1 replication. Center investigators are collectively focused on the structures, dynamics, interactions, and mechanisms of action of HIV-1 RNA during the late phase of viral replication.