The purpose of this study is to collect biological specimens to use for designing and improving research tests. Specimens include blood, stool, saliva, and skin/mucosal swabs.

The objective of this study is to learn how Staphylococcus aureus (S. aureus) interacts with cells in the body using tissues from tonsils discarded after standard surgery to remove them.

The purpose of this study is to investigate thymic development, survival, and trafficking of the mobilized human cells within murine lymphoid and non-lymphoid organs.

This study will investigate how, why and under what conditions eosinophils (a type of white blood cell) become activated and will examine their function in immune reactions.

The purpose of this study is to see if a drug called empagliflozin can help people with severe congenital neutropenia (SCN).

The purpose of this study is to screen volunteers for clinical trials for investigational or licensed vaccines or drugs to treat or prevent virus infections.

This purpose of this protocol is to evaluate selected patients with documented recurrent or unusual infections and their family members for clinical and laboratory correlates of immune abnormalities.

The purpose of this study is to understand the underlying immune dysregulation, identify the genetic cause, and to translate our findings into novel treatments that improve patients disease outcomes.

The objective of this study is to learn more about the interaction between immune and nervous system and how immunity disease affect the nervous system.

Researchers want to study samples from people with healthy immune systems and people with conditions that affect how the immune system works to learn more about the immune system and how immunological disorders predispose affected individuals to a myriad of complications, including infection, immune dysregulation with autoimmune disease and aberrant inflammatory responses, and malignancy.