Evaluating the Genetics and Immunology of Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis (PFAPA) Syndrome and Other Tonsil Disorders

The purpose of this study is to collect blood and other specimens from people with periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) to learn more about the illness.

Contact Information

Office/Contact: Srinivasalu Hemalatha
Phone: 202-476-2800
Email: HSriniva@childrensnational.org

Study of Factors Regulating Mast Cell Proliferation

This purpose of this study is to examine growth factors that promote and inhibit mast cell proliferation resulting in mastocytosis, a disease of excessive mast cells in the body.

Contact Information

Office/Contact: For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)
Phone: 800-411-1222
TTY: TTY dial 711
Email: ccopr@nih.gov
 

Host Response to Infection and Treatment in Filarial Diseases

This study will evaluate and treat patients with filarial infections to explore in depth the immunology of the disease, including susceptibility to infection, disease development, and response to treatment.

Respiratory Virus Sampling and Repository

The purpose of this study is to obtain samples from people with respiratory viruses to learn more about respiratory virus infections and the immune responses against them.

Contact Information

Office/Contact: For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)
Phone: 800-411-1222
TTY: TTY dial 711
Email: ccopr@nih.gov
 

NADPH Oxidase Correction in mRNA-transfected Granulocyte-enriched Cells in Chronic Granulomatous Disease (CGD)

The purpose of this study is to test a procedure in which messenger RNA (mRNA) is added to a persons blood cells.

Contact Information

Office/Contact: For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)
Phone: 800-411-1222
TTY: TTY dial 711
Email: ccopr@nih.gov

Metabolic Profiling of Immune Responses in Immune-mediated Diseases

The purpose of this study is to learn about how the immune system and skin healing are related to each other.

Contact Information

Office/Contact: For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)
Phone: 800-411-1222
TTY: TTY8664111010
Email: prpl@cc.nih.gov
 

Tyrosine Kinase Inhibition to Treat Myeloid Hypereosinophilic Syndrome

The purpose of this study is to evaluate the safety and efficacy of the tyrosine kinase inhibitor, imatinib mesylate (Gleevec ) in reducing peripheral blood eosinophilia in patients with the myeloid form of hypereosinophilic syndrome (HES).

Contact Information

Office/Contact: For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)
Phone: 800-411-1222
TTY: TTY dial 711
Email: ccopr@nih.gov
 

Detection and Characterization of Infections and Infection Susceptibility

The purpose of this study is to examine the causes of immune disorders affecting white blood cells, which defend against infections and will try to develop better means of diagnosis and treatment of these immune disorders.

Contact Information

Office/Contact: For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)
Phone: 800-411-1222
TTY: TTY dial 711
Email: ccopr@nih.gov
 

Cardamom and Topical Roseomonas in Atopic Dermatitis

The objective of this study is to test a skin treatment that contains Roseomonas mucosa and ground cardamom seeds in people with atopic dermatitis (AD).

Contact Information

Office/Contact: NIH Clinical Center Office of Patient Recruitment (OPR)
Phone: 800-411-1222
TTY: TTY dial 711
Email: ccopr@nih.gov
 

Screening Protocol for Genetic Diseases of Lymphocyte Homeostasis and Programmed Cell Death

The purpose of this study is to determine the biochemical and genetic causes of inherited immune diseases affecting lymphocyte homeostasis.

Contact Information

Office/Contact: For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)
Phone: 800-411-1222
TTY: TTY dial 711
Email: ccopr@nih.gov