Biocontainment Laboratory—University of Texas Medical Branch Galveston National Laboratory

Biocontainment Laboratory—Boston University National Emerging Infectious Diseases Laboratory

The National Emerging Infectious Diseases Laboratories (NEIDL) is one of two National Biocontainment Laboratories constructed under a grant from the National Institute of Allergy and Infectious Diseases. The mission of the NEIDL is to generate and translate fundamental knowledge on high priority emerging infectious diseases for the benefit of the public health, locally, nationally and globally.

National and Regional Biocontainment Research Facilities

The National Biocontainment Laboratories (NBLs) and Regional Biocontainment Laboratories (RBLs) provide BSL4/3/2 and BSL3/2 biocontainment facilities, respectively, for research on biodefense and emerging infectious disease agents.  

Diagnostics Development Services

NIAID’s Diagnostics Development Services program offers reagents, platform testing, and planning and design support to accelerate product development of in vitro diagnostics (IVD) for infectious diseases, from research feasibility through clinical validation.

Combating Antibiotic-Resistant Bacteria Interdisciplinary Research Units (CARBIRU)

The Combating Antibiotic-Resistant Bacteria Interdisciplinary Research Units (CARBIRUs) are multidisciplinary research centers focused on bacterial pathogens for which antibiotic resistance poses a significant public health concern, as designated by the CDC’s 2019 Report on Antibiotic Resistance Threats in the United States. Each center brings together investigators from multiple disciplines to investigate non-antibiotic alternative treatment and preventive strategies, including bacteriophage, monoclonal antibodies, ligand mimetics, and defined microbial consortia; poorly understood resistance mechanisms contributing to bacterial persistence and antibiotic treatment failure; and identification and validation of novel bacterial targets for antibiotic intervention.

Main Areas of Focus

The CARBIRU program supports fundamental, collaborative research ranging from discovery to early development research activities such as the:

  • Discovery and validation of viable therapeutic, diagnostic, or vaccine targets
  • Identification and characterization of host factors involved in susceptibility or response to infection and/or resistance
  • Elucidation of known or evolving mechanisms of antibiotic resistance and strategies to prevent emergence of resistance
  • Identification and development of novel approaches to combat antibiotic-resistant infections
  • Understanding the role of the microbiome and antibiotic-mediated dysbiosis in the development of resistant infections

Contact Information

Locations
Content Coordinator

Next Generation COVID-19 Vaccines

Project NextGen

Led by NIAID and the Biomedical Advanced Research and Development Authority (BARDA), part of the HHS Administration for Strategic Preparedness and Response (ASPR), Project NextGen is a coordinated effort where the federal government works with the private sector to advance the pipeline of new, innovative vaccines and therapeutics from labs into clinical trials with the intent to transition to the private sector later stage development and potential U.S.

Clinical Trial of mRNA Universal Influenza Vaccine Candidate Begins

A clinical trial of an experimental universal influenza vaccine developed by researchers at the National Institute of Allergy and Infectious Diseases’ (NIAID) Vaccine Research Center (VRC), part of the National Institutes of Health, has begun enrolling volunteers at Duke University in Durham, North Carolina. This Phase 1 trial will test the experimental vaccine, known as H1ssF-3928 mRNA-LNP, for safety and its ability to induce an immune response.

Contact

Submit a Media Request

Contact the NIAID News & Science Writing Branch.

301-402-1663
niaidnews@niaid.nih.gov
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NIAID Marks World Malaria Day

World Malaria Day is an opportunity to reflect on continuing challenges posed by malaria and reaffirm a commitment to overcoming them. The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, joins with the global health community in recognizing this year’s theme of “Time to Deliver on Zero Malaria: Invest, Innovate, Implement.”

Contact

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Contact the NIAID News & Science Writing Branch.

301-402-1663
niaidnews@niaid.nih.gov
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The Potential and Challenges of Mucosal COVID-19 Vaccines

In November 2022, the National Institute of Allergy and Infectious Diseases (NIAID) co-hosted a virtual workshop on the importance and challenges of developing mucosal vaccines for SARS-COV-2. The highlights of this workshop have now been published as a report in npj Vaccines.

Contact

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Contact the NIAID News & Science Writing Branch.

301-402-1663
niaidnews@niaid.nih.gov
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Temperature-Stable TB Vaccine Safe, Prompts Immune Response in NIH-Supported Study

A clinical trial testing a freeze-dried, temperature-stable experimental tuberculosis (TB) vaccine in healthy adults found that it was safe and stimulated both antibodies and responses from the cellular arm of the immune system. The Phase 1 trial was supported by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. A non-temperature stable form of the candidate previously had been tested in several clinical trials.

Contact

Submit a Media Request

Contact the NIAID News & Science Writing Branch.

301-402-1663
niaidnews@niaid.nih.gov
All Media Contacts