- Jeanne Marrazzo, M.D., M.P.H., Director
- Sarah W. Read, M.D., M.H.S., Principal Deputy Director
- H. Clifford Lane, M.D., Deputy Director for Clinical Research and Special Projects
- Jill R. Harper, Ph.D., Deputy Director for Science Management and Director, Office of Science Management and Operations
- Kimberly M. Barasch, Staff Assistant to the Director
- Lucas Buyon, Ph.D., Sc.M., Presidential Management Fellow
- Patricia L. Conrad, Special Assistant to the Director
- Robert W. Eisinger, Ph.D., Senior Advisor to the NIAID Director
- Sharon M. Gilles, Special Assistant to the Principal Deputy Director
- Tara N. Palmore, M.D., Senior Medical Advisor
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