Immunology Interest Group (IIG) Seminar Series Archive

Seminars are available for viewing by members only as follows:

2023-2024

DateSpeaker and AffiliationSeminar Title
Wednesday, September 13, 2023 Diane Mathis (Harvard) William E. Paul Lecture| Thymic Mimetic Cells: Tolerogenic Masqueraders 
Wednesday, September 20, 2023 Iliyan Iliev (Cornell) Immunity, hematopoiesis and cancer through the prism of the gut mycobiome 
Wednesday, October 4, 2023 Han-Yu Shih (NEI) Decoding Lymphocyte Regulomes in Neurodegeneration
Wednesday, October 11, 2023 Ben Afzali (NIDDK) Regulating tissue inflammation - from transcriptional regulators to effector molecules
Wednesday, October 18, 2023 Tim Sparwasser (Mainz) Metabolic checkpoints for T cell fate and function
Wednesday, October 25, 2023 Thierry Gauthier (NIDCR) Control of innate immune responses by members of the TGF-β superfamily of proteins
Wednesday, November 1, 2023Joseph A. Bellanti (Georgetown)CpG and Therapeutic Vaccines
Wednesday, November 8, 2023Jun Huh (Harvard)Unraveling regulation and unexpected role of Interleukin-17
Wednesday, November 29, 2023Judith Agudo (Dana Farber)Immune evasion of stem cells in health and cancer
Wednesday, December 6, 2023Joan Yuan (Lund)The role of early life origin B cells in adult immunity
Wednesday, December 13, 2023Barbara Baird (Cornell)How does the Plasma Membrane Participate in Receptor-Mediated Cell Signaling?
Wednesday, December 20, 2023Edward Pearce (Hopkins)Targeting immune cell metabolism with a view to altering disease outcome
Wednesday, January 3, 2024Brian S. Kim (Mt Sinai)Sensing Inflammation in the Skin and Beyond
Wednesday, January 10, 2024Mariana Kaplan (NIAMS)Neutrophils: acute responders in chronic inflammatory diseases
Wednesday, January 17, 2024Nicola Harris (Monash)The gut-lung axis: how perturbation of the microbiome influences allergic airway inflammation
Wednesday, January 24, 2024Antonio Lanzavecchia (INGM)WALS| Cancelled and will be rescheduled for next season
Wednesday, January 24, 2024Chrysothemis Brown (MSKCC)Early life imprinting of intestinal tolerance
Wednesday, February 7, 2024Julie Blander (Cornell)Harnessing Innate Immunity and Inflammasome Activation in Vaccines and Cancer Therapy
Wednesday, February 14, 2024Helen Su (NIAID)A new molecular regulatory pathway revealed by studying a human immunodysregulatory disorder
Wednesday, February 21, 2024Edward A. Fisher (NYU)Chronic psychological stress and macrophage inflammation in atherosclerosis
Wednesday, February 28, 2024Subash Babu (NIAID/ICER)Understanding Immune Responses in Strongyloides stercoralis Infection: Implications for Bystander Effects on Tuberculosis and Type 2 Diabetes
Wednesday, March 6, 2024Kathy McCoy (Calgary)Microbiome, metabolites and mucosal immunity
Wednesday, March 13, 2024Daniel Mucida (Rockefeller)A neuro-immune circuit regulates nocturnal oscillations in intestinal Tregs
Wednesday, March 20, 2024Joanne Reed (Garvan)Evolution of pathogenic autoantibodies and B cell clones
Wednesday, March 27, 2024
**3 – 4 pm**
Vishva Dixit (Genentech)Why so many ways to Die?
Wednesday, April 3, 2024Chris Hunter (UPenn)IL-27: King of Cytokines
Wednesday, April 10, 2024Betty Diamond (Feinstein)Neuropsychiatric lupus: a nonresolving inflammation
Wednesday, April 17, 2024Daniel Kaplan (Pittsburgh)Neuronal Control of Cutaneous Inflammation
Wednesday, April 24, 2024Manolis Pasparakis (Cologne)Cancelled
Wednesday, May 1, 2024Polly Matzinger (NIAID)The Danger model: are we cutting off too small a slice of the pie?
Wednesday, May 15, 2024De'Broski R Herbert (UPenn)Cancelled
Wednesday, May 22, 2024Andrea Reboldi (UMass)Intestinal IgA response: from generation to regulation
Wednesday, May 29, 2024Richard Grencis (Manchester)Resistance and susceptibility to intestinal helminths: from cross protective immunity to chronic infection
Wednesday, June 5, 2024Ivan Zanoni (Harvard)Molecular regulation of inflammation
Wednesday, June 26, 2024Caroline Sokol (MGH/Harvard)Neuroimmune circuits driving allergic immunity

2022-2023

DateSpeaker and AffiliationSeminar Title
Wednesday, September 14, 2022Vanja Lazarevic
NCI/NIH
Transcriptional regulation of CD4+ T cells that mediate neuroinflammation
Wednesday, September 21, 2022Catherine Wu
Dana-Farber Cancer Institute/Harvard University
Updates on personal cancer vaccines
Wednesday, September 28, 2022Michela Locci
University of Pennsylvania
Germinal center responses to messenger RNA vaccines
Wednesday, October 12, 2022Dan Littman, MD, PhD (NYU/HHMI)Unlocking the logic of microbiota-instructed T cell differentiation
Wednesday, October 19, 2022 - 2pmRon Germain, ScB, ScM, MD, PhD (NIH)William E. Paul Lecture | Gaining New Insights into 'Fundamental Immunology' Using Imaging and Computation
Wednesday, October 26, 2022Coleen McNamara, MD (UVA)The B-side of Atherosclerosis
Wednesday, November 2, 2022Michelle Linterman (Babraham Institute)Lost in space: How ageing changes the immune response to vaccination.
Wednesday, November 9, 2022Claudia Kemper (NIH)New tricks from a very old dog – the complosome as orchestrator of normal cell physiology
Wednesday, November 16, 2022Marco Colonna (Washington University in St. Louis)TREM2 signaling in neurodegeneration and cancer
Wednesday, November 30, 2022David Sancho (CNIC)Connecting myeloid cell metabolism and function
Wednesday, December 7, 2022Julie Zikherman (UCSF)Balancing tolerance and immunity downstream of the antigen receptor
Wednesday, December 14, 2022Jonathan Kagan (Harvard)Initiation and Regulation of Innate Immunity
Wednesday, December 21, 2022Sergio Pontejo (NIH)Chemokines and anionic phospholipids: new binding partners for microbial killing and apoptotic cell clearance
Wednesday, January 4, 2023Barbara Kee (University of Chicago)Transcriptional Control of Innate Lymphocyte Development and Function
Wednesday, January 11, 2023Klaus Frueh (OHSU)The unique immune biology of cytomegalovirus-based vaccines
Wednesday, January 18, 2023Victor Torres (NYU Langone Health)Mammalian DNases and their role in the tug of war between Staphylococcus aureus and the host
Wednesday, January 25, 2023Gabriel Victora (The Rockefeller University)Clonal dynamics of the recall antibody response
Wednesday, February 1, 2023Andres Hidalgo (Yale)Diversity of neutrophils
Wednesday, February 8, 2023Matthew Krummel (UCSF)Identifying and Modulating Immune Archetypes in Cancer and Beyond
Wednesday, February 15, 2023Fathia Mami-Chouaïb (Gustave Roussy)Tissue-Resident Memory T (TRM) cells in cancer
Wednesday, February 22, 2023Cynthia Dunbar (NIH)Lineage tracking in rhesus macaques: new insights into natural killer cells and tissue-resident myeloid cells
Wednesday, March 1, 2023Roi Gazit (Ben-Gurion University of the Negev)Exciting Hematopoietic Stem Cells
Wednesday, March 8, 2023Maria Yazdanbakhsh (Leiden University)Modulation of immune responses by exposure to environments rich in microorganisms and parasites
Wednesday, March 15, 2023Cornelia Bergmann (Cleveland Clinic)Interferons and TREM2 as regulators of murine neurotropic coronavirus pathogenesis
Wednesday, March 22, 2023Ann Chahroudi (Emory University)Viral reservoirs and rebound in a model of perinatal HIV infection
Wednesday, March 29, 2023Muzlifah Haniffa (Newcastle University)Decoding the developing human immune system
Wednesday, April 5, 2023Michal Bassani-Sternberg (University of Lausanne)The tumor antigenic landscape associated with T cell infiltration and immunoediting
Wednesday, April 12, 2023Nobuhiko Kamada (University of Michigan)Pathogenic communications between the mouth and gut
Wednesday, April 19, 2023Tobias Hohl (Memorial Sloan Kettering Cancer Center)The Last of Us: foiling fungi in the air and in the microbiota
Wednesday, May 3, 2023Gwendalyn Randolph (Washington University in St. Louis)Phagocyte and vascular features of the immunological landscape in the gut-mesenteric-peritoneal space
Wednesday, May 10, 2023Henrique Veiga-Fernandes (Champalimaud Foundation)Neuroimmune Ecosystems
Wednesday, May 17, 2023Enfu Hui (UCSD)Unconventional signaling of CD28 and CTLA4: when their ligands get onto T cells
Wednesday, May 24, 2023Eric Vivier (Aix-Marseille University)Harnessing Natural Killer cells in cancer therapies
Wednesday, May 31, 2023Richard Gallo (UC San Diego)Antimicrobial Peptides, the Microbiome and Human Health
Wednesday, June 7, 2023Neil Henderson (The University of Edinburgh)Multimodal decoding of liver regeneration and repair
Wednesday, June 14, 2023Nicole Joller
(University of Zurich)
Heterologous Immunity: How Infection History affects Inflammatory Diseases
Wednesday, June 21, 2023Eric Huseby (UMass Med)MHC-II heterozygosity limits T1D susceptibility through non-cognate negative selection
Wednesday, June 28, 2023Eui-Cheol Shin (Korea Advanced Institute of Science and Technology)IL-15-induced bystander T cell activation in human viral disease
Wednesday, July 5, 2023Guillaume Gaud (NIH)CD3z ITAMs mediate TCR ligand discrimination
Wednesday, July 12, 2023Chuan Wu (NIH)Immune calibration of neuroendocrine homeostasis

2021-2022

DateSpeaker and AffiliationSeminar Title
Wednesday, Sept. 22, 2021Samuel Katz, SIG FARE
National Institutes of Health (NIH)
Novel approaches for high-throughput analysis reveal alternative splicing as a critical regulator of macrophage activation
Wednesday, Sept. 29, 2021John Tsang
NIH
Do differences make a difference: integrating human immune health and single cell variations
Wednesday, Oct. 6, 2021Ethan Shevach
NIH
Counterintuitive Immunology: Enhancement of Immune Responses by Blocking MHC I or MHC II
Wednesday, Oct. 13, 2021Kenneth Cadwell
New York University
Host adaptations to microbial diversity
Wednesday, Oct. 20, 2021Pamela Bjorkman
Caltech
Neutralizing antibodies against coronaviruses
Wednesday, Oct. 27, 2021Miriam Merad
Mount Siani
Mapping suppressive myeloid programs in the tumor microenvironment
Wednesday, Nov. 3, 2021Christoph Hess
University of Cambridge
Metabolic control of T cell co-stimulation
Wednesday, Nov. 10, 2021John Wherry
University of Pennsylvania
Immunological Memory to SARS-CoV-2 mRNA vaccination
Wednesday, Nov. 17, 2021Claude Perreault
University of Montreal
Discovery of Actionable Tumor Antigens
Wednesday, Dec. 1, 2021Hedda Wardemann
Heidelberg
Guiding malaria vaccine design through functional antigen-receptor repertoire studies
Wednesday, Dec. 8, 2021Brigitta Stockinger
Francis Crick
Environmental input in intestinal tissue repair
Wednesday, Dec. 15, 2021John O'Shea, Bill Paul Lecture
NIH
Cytokine Signaling: The more things change the more they stay the same
Wednesday, Jan. 5, 2022Kristin Hogquist
University of Minnesota
'The thymus: a raucous nursery'
Wednesday, Jan. 12, 2022Deborah Fowell
Cornell University
T cell activation niches in inflamed tissues
Wednesday, Jan. 19, 2022Marion Pepper
University of Washington
Imprinted SARS-CoV-2-specific memory lymphocytes define hybrid immunity
Wednesday, Jan. 26, 2022Melody Swartz
University of Chicago
Immunoregulatory roles of lymphatic vessels in cancer and opportunities for immunoengineering
Wednesday, Feb. 2, 2022Jennifer Gommerman
University of Toronto
Fantastic IgA plasma cells and where to find them
Wednesday, Feb. 9, 2022Margaret Ackerman
Dartmouth College
Maternal antibody interventions to prevent early life infection
Wednesday, Feb. 16, 2022Greg M. Delgoffe
University of Pittsburgh
Metabolic liabilities and opportunities in cancer immunology
Wednesday, Feb. 23, 2022Philippa Marrack
National Jewish Health
The repertoire of T cells bearing TCR alpha/beta receptors
Wednesday, March 2, 2022Nicola Ternette
University of Oxford
Driving antigen discovery by integrating proteogenomics and de novo peptide sequencing strategies
Wednesday, March 9, 2022Catherine Blish
Stanford
Modeling COVID-19 immunopathogenesis in vivo and in vitro
Wednesday, March 16, 2022Montserrat Anguerra
University of Pennsylvania
Understanding genetic contribution for female-biased disease: X-Chromosome Inactivation in immune cells
Wednesday, March 23, 2022Arthur Weiss
University of California, San Francisco
Unique features in the TCR signaling pathway for recognition of weak ligands and for ligand discrimination
Wednesday, March 30, 2022Ronen Alon
Weizmann Institute
Integrin signals for lymphocyte differentiation and effector functions: facts and puzzles
Wednesday, April 6, 2022Susan Kaech
Salk
Co-opting tissue resident macrophages in cancer
Wednesday, April 13, 2022Alessandro Sette
Lo Jolla Allergy Institute
Adaptive responses to SARS CoV2 infection and vaccination
Wednesday, April 20, 2022Graham Anderson
University of Birmingham
Thymus Generation and Regeneration
Wednesday, April 27, 2022Richard Flavell
Yale
Mechanisms of pathogenesis revealed by a humanized model of COVID-19
Wednesday, May 4, 2022Florent Ginhoux
STAR
Macrophage Biology: From Development to Disease
Wednesday, May 18, 2022Peng JiangBig Data Approaches to Study Intercellular Signaling in Cancer Immunotherapy Resistance
Wednesday, May 25, 2022Garry Nolan
Stanford
Cancer rearranges the rules in tissue building blocks.  A new class of targets for therapy?
Wednesday, June 1, 2022Joonsoo Kang
University of Massachusetts
Regulation of mucocutaneous inflammation and innate lymphocytes by cholesterol metabolites
Wednesday, June 8, 2022Akiko Iwasaki
Yale
Immune response to SARS-CoV-2
Wednesday, June 15, 2022Gillian Griffiths, WALS
University of Cambridge
Identifying novel genes that impact T cell effector function
Wednesday, June 22, 2022Niki Moutsopolous
NIDCR
Fibrin is a critical regulator of neutrophil effector function in the mucosal tissue microenvironment

2020-2021

DateSpeakerSeminar Title
Wednesday, Sept. 23, 2020Elina Zuniga
University of California, San Diego
Type I Interferon Induction and Exhaustion upon Viral Infection
Wednesday, Sept. 30, 2020Caetano Reis e Sous, WALS
Crick
DaNGeRous Indigestion and Immunity to Cancer
Wednesday, Oct. 7, 2020Michel Nussensweig, Bill Paul LectureHuman Antibody Responses to SARS-CoV-2
Wednesday, Oct. 14, 2020Harikesh Wong
NIAID
Multicellular Control of Immunological Homeostasis
Wednesday, Oct. 28, 2020David Artis
Cornell
Immune Regulation at Barrier Surfaces
Wednesday, Nov. 4, 2020Stefan Feske
New York University
Ion channels regulating immunity: ORAI, STIM et al.
Wednesday, Nov. 18, 2020Georg Holländer
Oxford
The rise and fall of the thymus: A molecular perspective
Wednesday, Dec. 2, 2020Mihalis Lionakis
NIAID
Aberrant type 1 immunity drives susceptibility to mucosal fungal diseas
Wednesday, Dec. 9, 2020Naomi Taylor
National Cancer Institute (NCI)
Metabolite shifts at the crossroads of T cell and myeloid/erythroid progenitor differentiation
Wednesday, Dec. 16, 2020Mike Dustin
Oxford
T cells on the attack against cancer and infection
Wednesday, Jan. 6, 2020Ken-ichi Hanada
NCI
Single-cell Analysis of Fresh Human Lung Cancers Allows Rapid Cloning of Neoantigen-reactive T-cell Receptors
Wednesday, Jan. 13, 2021Chiara Romagnani
DRFZ
T-bet controls lymph node formation by regulating differentiation of fetal innate lymphoid cells (ILC)
Wednesday, Jan. 27, 2021Virginia Pascual
Cornell
Human SLE: a complex interferonopathy
Wednesday, Feb. 3, 2021Steve Jameson University of MinnesotaICOS engagement promotes establishment of CD8+ resident memory T cells
Wednesday, Feb. 10, 2021Menna Clatworthy
Cambridge
B cells and antibodies - uncovering unexpected roles in homeostasis, autoimmunity and defense
Wednesday, Feb. 17, 2021Leslie Berg
University of Colorado
Linking TCR Signaling to Variations in Gene Expression
Wednesday, Feb. 24, 2021Talal Chatila
Harvard
License to Inflame: Notch4 Treg Cells in Allergic and Viral Lung Diseases
Wednesday, March 3, 2021Jeffrey Rathmell
Vanderbilt
Fueling T cells: Immunometabolic Checkpoints in Cancer & Inflammation
Wednesday, March 10, 2021Laura Chopp
NCI
E pluribus unum: deciphering T cell development from single-cell transcriptome and chromatin analyses
Wednesday, March 17, 2021Steffen Jung
Weizmann Institute
Probing brain macrophage functions
Wednesday, March 24, 2021Gérard Eberl
Pasteur
Imprinting and regulation of the immune and nervous systems by microbiota
Wednesday, March 31, 2021Chuan Wu
NCI
Immune-neural transmission regulates gut sensation
Wednesday, April 7, 2021Luisa DiPietro
University of Illinois, Chicago
The healing wound:  How apoptosis, phagocytosis, and scar formation intersect in the closing chapter
Wednesday, April 14, 2021Noah Palm
Yale
Mapping uncharted landscapes of host-microbiota connectivity
Wednesday, April 21, 2021Janis Burkhardt
University of Pennsylvania
The T cell actin cortex:  New insights into homeostatic trafficking and immunodeficiency
Wednesday, April 28, 2021Shannon Turley
Genentech
Stromal evolution in cancer and immunotherapy
Wednesday, May 5, 2021Christina Leslie
Sloan-Kettering
Decoding T cell dysfunction and the tumor immune microenvironment
Wednesday, May 19, 2021Susan Carpenter
University of California, Santa Cruz
How do long noncoding RNAs function to control inflammation?
Wednesday, May 26, 2021Virginia Shapiro
Mayo Clinic
Regulation of T cell development and activation by HDAC3
Wednesday, June 2, 2021Richard Locksley
University of California, San Francisco
Innate Allergy and Tissue Resilience
Wednesday, June 9, 2021Frances Lund
University of Alabama
Inflammatory cytokine-mediated control of effector and memory B cell development and function
Wednesday, June 16, 2021Ananda Goldrath
University of California, San Diego
Transcriptional programming of CD8 T cell responses to infection and malignancy
Wednesday, June 23, 2021David Underhill
Cedars Sinai
Innate and Adaptive Immunity to the Mycobiome in Crohn’s Disease
Wednesday, June 30, 2021Juan Carlos Zuniga-Pflucker
University of Toronto
Teaching New Tricks to an Old Thymus
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