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Training Grants (T)

For applications due on or after January 25, 2025, NIH will implement Updates to NIH Institutional Training Grant Applications designed to streamline the application process, strengthen mentor training, and improve peer review.

Table of Contents

Overview

National Research Service Award (NRSA) Institutional Research Training Grants (T32) provide domestic, nonprofit, and private or public graduate-level academic institutions with funds for training predoctoral and postdoctoral candidates.

Senior investigators who head research or training programs at an institution generally apply for these grants. Trainee-level investigators should contact their institution about training opportunities.

Trainees must be U.S. citizens, noncitizen nationals, or permanent residents with a valid Alien Registration Receipt Card (Form I-551). People on temporary or student visas are not eligible.

For Some Grants, You'll Owe Work Time

Postdoctoral trainees on T32 grants must repay the government for their grant support. This isn't like paying off a loan; your debt is one of time and effort, not money. You can pay it off by continuing to work on the project for which you were funded.

During the first year of your appointment, you'll owe one month of payback for every month you're supported by NIH funds. After the first year, you can start paying back. For every month you continue to work—even with funding—you pay back one month of your debt. If your training lasts two years, your obligation will be paid in full.

If You Can't Pay Back With Work

If your project loses funding after the first year, you can complete your payback through continued research or teaching on at least a half-time basis (20 hours per week). Unless there are serious extenuating circumstances, you must complete the payback within two years after termination of support.

If you fail to repay your obligation within two years, you'll owe the government the full amount of your grant, plus interest. If you don't perform the research or teaching necessary for payback, make sure you'll have the money to reimburse the government for your grant.

How Long Does Support Last?

NIAID awards T32s for 5 years, with the chance to renew. We make awards annually, capped at 8 training slots per year, with further support contingent on performance and funding availability. Check notice: NOT-AI-24-052: NIAID T32 Training Grants Maximum Number of Trainee Slots.

Trainee appointments are usually in 1-year increments; new appointments must be at least 9 months except when we've approved a short-term training position. A trainee can remain in a program for a maximum of 5 years for predoctoral trainees; 3 years for postdoctoral trainees.

For more details, see the trainee appointments section of T32 Training Grants—Key Administrative Information.

What Do Training Funds Pay For?

T32 grants provide funds for:

  • NRSA Stipends
  • Tuition and fees, trainee travel, and training-related expenses—For details, refer to What Do Training Grants Pay For? on Salary Cap, Stipends, & Training Funds.
  • On a case-by-case basis, institutional costs for accommodating disabled trainees in addition to usual costs paid by training-related expenses.
  • Childcare costs—NRSA childcare costs apply to full-time predoctoral and postdoctoral trainees appointed on NRSA institutional research training awards. Each full-time predoctoral or postdoctoral NRSA appointed trainee will receive $3,000 per budget period for childcare costs provided by a licensed childcare provider.

Note on effort requirement: Trainee appointments require full-time effort, 12 person months a year. In addition to the full-time training, trainees may spend on average, an additional 25 percent of their time (e.g., 10 hours a week) in part-time research, teaching, or clinical employment, so long as those activities do not interfere with, or lengthen, the duration of their NRSA training.

Qualifying for a Training Grant

A successful institutional candidate for a training grant must provide an outstanding research and academic environment, with suitable staff and facilities.

The institution's proposed training program director must be an established, well-recognized scientist, generally with the rank of professor or equivalent, who offers a long training track record.

Another key element is a critical mass of fairly senior scientists in the research area who can demonstrate a publications history and funding from NIH, NSF, HHMI, or similar agencies. Too many junior scientists or those without grants may negatively influence the overall impact score and chances of funding.

Peer reviewers consider the records of past trainees or graduates, who should demonstrate strong academic ability.

Successful applicant institutions offer a track record of past trainees who publish, obtain funding, and enjoy distinguished scientific positions. Reviewers highly rate an adequate supply of high-quality potential trainees with genuine interest in research and appropriate academic prerequisites.

To learn more about training grant requirements, Search for NIAID T32 Funding Opportunities.

What Are Your Chances of Succeeding?

Find success rates for T32s at Success Rates on NIH RePORT.

For more data and statistics, go to NIH's Extramural Training Mechanisms.

When to Apply for NIAID T32 Awards

Follow the NIAID-specific rules and guidance in the two sections below for training grant (T) applications.

Application Timing Policy

Follow NIAID’s timing policy. We accept T applications only twice annually:

  • Non-AIDS: January 25 and September 25 for new, resubmission, and renewal applications.
  • AIDS-related: January 7 and May 7 for new, resubmission, and renewal applications.

NIAID’s timing is an exception to the typical NIH schedule of three standard annual due dates. Other NIH institutes and centers may support different due dates. Refer to the table of IC-specific information listed in the notice of funding opportunity.

Target Due Dates for Competing Renewal (Type 2) T Applications

If you have an existing NIAID T32 grant (Type 5) and plan to apply for a competing renewal (Type 2), we strongly encourage you to use Table 1 below to calculate the earliest target due date for your Type 2 application.

If you submit your Type 2 application for the due date indicated in Table 1, it will minimize the hiatus between the end of your Type 5 and start of your potential Type 2 award.

Table 1. Earliest Target Due Date for Your NIAID Renewal (Type 2) T Application

Your Type 5 End DateEarliest Target Due Date for Your Type 2 Application
January through September

Non-AIDS: January 25 of the previous calendar year

AIDS-related: May 7 of the previous calendar year

October through December

Non-AIDS: January 25 of the same calendar year

AIDS-related: May 7 of the same calendar year

Resist any temptation to target an even earlier due date for your renewal application. NIAID cannot fund two awards for the same program in the same fiscal year (FY) or save your too-early application for funding in the next FY.

You may submit your renewal for the date indicated in Table 1 or target any subsequent NIAID due date. (Later due dates are more likely to lead to a hiatus between awards.) Find NIAID’s annual due dates in the Application Timing Policy section above.

To confirm when you should apply, email AITrainingHelpDesk@mail.nih.gov.

Writing a Training Grant Application

Before you begin writing your application, carefully read the relevant notice of funding opportunity below and follow the supplemental instructions for T applications in the SF 424 Application Guide, including guidelines for page limits and items allowed for the Appendix.

Successful training grant applications require different elements than do R01s. You must convince peer reviewers of your program's value by showing evidence of exceptional faculty commitment, resources, program design, training environment, and ability to recruit quality candidates. You should err on the side of self-promotion, rather than leaving out information that could help your case.

In assigning an application's overall impact score, reviewers will address and consider the following five criteria:

  1. Training Program and Environment
  2. Training Program Director/Principal Investigator (PD/PI)
  3. Preceptors/Mentors
  4. Trainees
  5. Training Record

Note: Institutional training program applications are undergoing changes that take effect for submissions due on or after January 25, 2025. For more details refer to Updates to NIH Institutional Training Grant Applications.

Changes include:

  • Update the Data Tables to reduce applicant and reviewer burden.
  • The Recruitment Plan to Enhance Diversity will become its own attachment instead of part of the 25-page program plan.
  • Include training in the Responsible Conduct of Research and Recruitment Plan to Enhance Diversity as items that contribute to the overall impact score.
  • Enhance research training programs by further defining expectations for mentor training and clarifying positive outcomes related to preparing trainees for the breadth of research and related careers relevant to the NIH mission.

For more detail on these criteria, refer to the Institutional Research Training Grants (T32) notice of funding opportunity.

Demonstrate Quality Program Design

Reviewers will assess the quality of your training program. They'll expect clear objectives and a thorough program design that shows your foresight, competence, and understanding of what a research program entails. Specify the features of the program, special seminar series, and postdoc rotations.

Training grants pay mostly for trainees, so you'll need evidence of a committed faculty, courses, and high-quality, readily available facilities and resources. You'll also need a trainee pool with the academic credentials to become distinguished researchers. Describe in detail your selection criteria for trainees.

Showcase Your Successes

Discuss the accomplishments of your former trainees, such as grants or fellowships awarded, other training appointments, promotion to scientific positions, publications, or patents received.

Ideally, your program produces many solid researchers who remain in their field. If not, other program strengths can compensate for some weaknesses in past trainees, especially if your program is relatively new.

Plan for Recruiting Trainees From Underrepresented Groups

Your application must include program-specific plans for recruiting trainees from underrepresented groups; general institution plans aren't sufficient.

Document your program's previous recruitment efforts among underrepresented groups, including successful and unsuccessful strategies. The best plans include personal recruitment efforts by the program director or faculty.

Include statistics on your program's current distribution of students from underrepresented groups who applied for admission or a position in the department relevant to the training grant, were offered admission or a position, enrolled in an academic program, or were appointed to the research training grant.

For more information about recruitment plans, go to NIH Research Training and Career Development Frequently Asked Questions. Also check Section 11.3.3.4 Recruitment Plan to Enhance Diversity in the NIH Grants Policy Statement.

Document Training on Responsible Conduct of Research

Your application must include a plan to offer trainees Training in the Responsible Conduct of Research. If you fail to include one, your application will be considered incomplete and won't be reviewed until you provide an acceptable plan of instruction. See the Responsible Conduct of Research—Training SOP and HHS Office of Research Integrity--General Resources for more information.

NIH requires additional training documentation for human subjects research. See the Document Training in the Protection of Human Subjects section of NIAID’s Research Using Human Subjects.

Describe how your institution will ensure that trainees participate only in 1) exempt human subjects research or non-exempt human subjects research that has institutional review board (IRB) approval, and 2) vertebrate animal research that has institutional animal care and use committee (IACUC) approval. Include this information in the "Human Subjects" or "Vertebrate Animals" section of the PHS 398 Research Training Program Plan form, respectively.

Include a Plan for Instruction in Methods for Enhancing Reproducibility

Individuals are required to comply with the instructions for the Plan for Instruction in Methods for Enhancing Reproducibility as provided in the SF 424 (R&R) Application Guide, which include a description of how the program will provide training in scientific reasoning, rigorous research design, relevant experimental methods, consideration of relevant biological variables such as sex, authentication of key biological and/or chemical resources, quantitative approaches, and data analysis and interpretation, as appropriate to the field study and the level and prior preparation of the trainees.

Harassment and Discrimination Protections

As part of your Letters of Support, include a letter on institutional letterhead signed by the president, the provost, a dean, or another key institutional leader with institution-wide responsibilities that describes institutional commitment to 1) ensuring proper policies, procedures, and oversight are in place to prevent discriminatory harassment and other discriminatory practices and 2) the planned training program to ensure its success. Check the Research Training Grants SOP for more information.

Comply With NIH Public Access Policy

Be sure to follow NIH public access policy, which includes citing peer-reviewed journal articles you have authored or coauthored and that resulted from an NIH-funded award. See the Public Access of Publications SOP for details. List your publications in the Biographical Sketch.

For renewal applications, you will report on publications during the just-in-time process for work conducted by trainees supported by the training grant, instead of in the "Progress Report" section of the PHS 398 Research Training Program Plan form.

Know NIH Rigor and Reproducibility Requirements

Be sure to address rigor and reproducibility. Check the requirements on the NIH Enhancing Reproducibility Through Rigor and Transparency page.

Applying for a Training Grant

Submit your application electronically using the NIH Application Submission System and Interface for Submission Tracking (ASSIST) or another of the NIH Submission Options. Check with your business office to see what approach it uses. Follow the instructions in your notice of funding opportunity and the supplemental instructions for T applications in the SF 424 Application Guide.

NIAID accepts training grant applications on January 25 and September 25 for non-AIDS and January 7 and May 7 for AIDS-related, an exception to the regular NIH schedule of three annual receipt dates. Other ICs may have different due dates.

After initial peer review in February or March, our Advisory Council will review your application in May or June. If you're successful, your award will start July 1 or later.

For an overview of the peer review process and to learn about review criteria so you can create a strong application, read Understand the Review Process.

Sending Materials Post-Submission

You may send certain materials after you have submitted your application and before initial peer review. For more information, refer to Allowable Post-Submission Materials.

Send three pages or fewer to your scientific review officer at least 30 days before the review meeting. Include a note from your business office stating its concurrence or ask your authorized organizational representative to send the information on your behalf.

For more on the post-submission materials policy, go to NIH's Post-Submission Materials Policy Frequently Asked Questions.

Submitting Your Training Grant Forms, Contacting NIAID

Use xTrain to submit all forms except payback agreements.

Online With xTrain

For trainees who do not require a payback agreement, submit the appointment form through xTrain in the eRA Commons. Also prepare and submit termination notices through xTrain.

To create and submit appointments, re-appointments, amendments, and terminations using xTrain, you must have an eRA Commons account. For information on how to get one, check eRA’s Create and Manage an eRA Commons Account.

You should also review instructions and training resources on the xTrain website, and the eRA Training - xTrain website.

You may also download and print payback agreements from xTrain, but for postdoc trainees you will need to send us an original, signed agreement. Check the next section for more information.

Quick Facts on Research Training Awards

Award Type

Search for NIAID T32 Funding Opportunities.

Award Specifics

Grant is up to 5-year duration, with the chance to renew. NIAID awards T32s annually, with a cap of 8 training slots per year.

Funding includes

  • NRSA Stipend Levels
  • Trainee travel
  • Institutional training-related expenses
  • Facilities and administrative costs based on 8 percent of modified total direct costs.
  • Trainees must devote full-time effort during the trainee appointment period.
  • On a case-by-case basis, institutional costs for accommodating disabled trainees in addition to usual costs paid by training-related expenses.
  • Childcare costs – NRSA childcare costs apply to full-time predoctoral and postdoctoral trainees appointed on NRSA institutional research training awards. Each full-time predoctoral or postdoctoral NRSA appointed trainee will receive $3,000 per budget period for childcare costs provided by a licensed childcare provider.

Applicant Profile

Domestic, non-profit, private, or public educational institution with an outstanding research and academic environment, including suitable staff and facilities.

Senior investigators who head research or training programs generally apply for T32s on behalf of their institution.

Application

Requires different elements than R01s. Institution must show

  • Clear objectives and quality training program, including special features (e.g., lab rotations, seminar series, entrance requirements; advisory committee).
  • Proposed training program director who is a well-recognized scientist with a long training track record.
  • Senior-level faculty with publications history, grants from NIH or similar agencies, and training experience.
  • Successful past trainees.
  • Adequate source of trainees.
  • T32-specific diversity recruitment plan.
  • Course on responsible conduct of research.

In preparing applications, institutions should use the Data Tables.

T32 Training Grants—Key Administrative Information

Receipt Dates

  • Noncompeting award (progress report). Research Performance Progress Report (RPPR) is due 4 months before the grant start date (e.g., if the start date is July 1, the progress report would be due March 1). For T32 RPPRs, create required training data tables using the Extramural Trainee Reporting and Career Tracking (xTRACT) module in the eRA Commons. For more information, refer to xTRACT Resources.
  • New or renewal competing applications. NIAID has two annual submission deadlines for T32 training grant applications: January 25 and September 25 for non-AIDS applications, and January 7 and May 7 for AIDS-related applications. Apply electronically and follow the supplemental instructions for training grants in the SF 424 Application Guide.

Carryover Authority

  • You do not need NIAID approval to rebudget funds, i.e., move funds from one budget category to another. You do need Prior Approval:
    • For restricted categories: stipends, tuition, fees (includes health insurance if awarded as part of this budget category)
    • To extend the last budget period of the project period up to 12 months
  • You must have Prior Approval to carryover unobligated balances.
    • Submit a written request signed by your business official.
    • Include a detailed budget and a strong justification for why the carryover funds are needed.
      • Program and grants management staff will review requests.
      • If they approve, the grants management specialist will issue a revised award authorizing the carryover.

Trainee Appointments

  • New trainees must be initially appointed for at least 9 months. 
  • You may not appoint new trainees during a no-cost extension without prior written approval from the Grants Management Program. Reappointments do not require prior approval.
  • New NRSA postdocs must sign a PHS-6031 payback agreement form.
    • Submit it with the PHS-2271.
    • Payback service is required for the first 12 months of support and may be fulfilled through an additional 12 months of T32 (or F32 postdoc fellowship) support.
  • Postdocs who participate in a project for at least 1 person month need to have an eRA Commons ID.
  • Predocs incur no payback obligation and do not sign a payback agreement.
  • Only U.S. citizens, non-citizen nationals, and permanent U.S. residents may be appointed to a T32.
    • Trainees who do not have this status must have a valid Alien Registration Receipt Card (I-551).
    • Send a notarized statement verifying permanent residency status with the PHS-2271.
    • Anyone on a temporary or student visa is not eligible.
  • Trainees may be appointed to the training grant on any day during the budget period including the last day.
  • Federal Financial Reports
    • Trainee costs are for the full 12-month appointment from the budget period in which the appointment began, even if an appointment extends beyond it.
      • Report funds for trainees with appointments extending beyond the budget period as unliquidated obligations.
      • If they are incorrectly reported as unobligated obligations, NIAID will use them to offset the future year award, and you will not have enough funds to support the trainees' costs in the grant year for which you submitted a Federal Financial Report.
  • Check NRSA Stipend Levels.
    • Postdocs receive the stipend level according to their experience, usually calculated from the date of the first doctoral degree.
    • Levels may change from one fiscal year to the next.
  • You may appoint one additional trainee over the number awarded (pre- and postdoctoral if a pre- and postdoctoral training program) without NIAID approval.
    • For more, you must obtain prior written approval from the Grants Management Program.
    • NIAID does not allow more than two additional trainees over the number awarded.
  • By rebudgeting, you may substitute one predoc for one postdoc or vice versa in a combined predoc and postdoc training program without NIAID approval.
  • Short-term summer trainee slots require a Statement of Appointment (PHS-2271).

Things to Do After Award

  • Use the xTrain module in the eRA Commons to create and submit appointments, re-appointments, amendments, and terminations.
    • Trainees supported by institutional research training awards that require appointments through the xTrain system must have an ORCID iD (Open Research and Contributor Identifier) and associate it with their eRA Commons Personal Profile. For instructions on how to create an ORCID iD, check eRA’s The ORCID ID instructions.
    • Send NIAID trainee appointment forms (PHS-2271) using xTrain no later than 3 months before the start of the next budget period, regardless of a trainee's appointment date. For example, all PHS-2271 are due April 1 for a T32 with an anniversary date of July 1.
      • You can appoint trainees up to the last day of the budget period, but we need the PHS-2271 by the due date. Call the grants management specialist listed in the eRA Commons if there are extenuating circumstances for not meeting the due date.
      • If your PHS-2271s are not received by the due date, NIAID will not be able to issue the Notice of Award for the upcoming year and may delete unfulfilled slots from all future years.
      • If you're having difficulty filling slots, contact your grants management specialist before this deadline.
    • Submit a Termination Notice (PHS-416-7) through xTrain for each trainee immediately when they terminate from a T32.
      • We must have the trainee's home address and phone number for tracking purposes.
      • Postdocs with a payback obligation must notify the Payback Service Center at 301-594-1835 of any change in address or phone number.
    • For training on using xTrain, visit eRA's xTrain training website.
  • Check the Research Training Grants SOP for instructions and details on payback agreements for postdoctoral trainees, which must be mailed to:
    • Yoon-Sun Webster
      Program Specialist 
      NIH/NIAID/DEA/GMP
      5601 Fishers Lane, RM Hoteling, MSC 9833
      Rockville, MD 20852
      Overnight Mail Only: Use Zip 20852

Contact Yoon-Sun Webster if you have questions about submitting Statement of Appointment forms or payback agreements. 

  • Report finances and expenditures.
    • Send a Federal Financial Report (FFR) annually, no later than 90 days after the end of the calendar quarter in which the budget period ends. The final report is due no later than 120 days after award end.
    • Reports of expenditures are required as documentation of the financial status of grants according to the official accounting records of the recipient organization.
    • You must submit financial reports electronically through the eRA Commons.
    • Failure to submit an FFR on time will delay NIAID issuing renewal and noncompeting awards.
    • Failure to submit complete, accurate, and timely reports may indicate the need for closer monitoring and possible enforcement actions by NIH.
    • Read more information regarding FFR filing in the NIH Grants Policy Statement.
  • Comply with the NIH Public Access Policy.

Trainee, scholar, and participant publications fall under the public access policy if the publication resulted from work conducted while the individual was supported by the award.

Have Questions?

Email AITrainingHelpDesk@mail.nih.gov, NIAID Research Training Officer, with any questions about our training grant programs.

For grants management questions about training grants, contact Regina Kitsoulis.

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